Scientists at McGill University (Canada) have developed a new injectable biomaterial that can repair damaged vocal cords and possibly restore voice to patients. The study results were published in the journal Biomaterials.
This is a so-called compressible hydrogel, a degradation-resistant material that can promote tissue regeneration.
The hydrogel is based on alginate, a natural polymer derived from brown algae. It is widely used in medicine due to its softness and high biocompatibility. The gel also contains an extracellular matrix, a complex of molecules that surrounds tissue cells and provides support, nourishment and repair.
Using compressible chemistry technology, the researchers were able to fine-tune the hydrogel's characteristics, from its breakdown time in the body to its degree of biocompatibility. In animal and cell model tests, the hydrogel promoted the formation of new blood vessels, reduced inflammation and fully integrated with the surrounding tissue over time.
The authors note that in the future, this development could be used not only to treat vocal cords, but also to repair other damaged soft tissues after surgery or trauma. The scientists also added that the new substance maintains its properties even after multiple injections, which could reduce the consumption of the substance and the potential cost of therapy.
Translation by Euromedia24.com
