Pekin University Hospital and Harvard T.H. Scientists of Chan's Public Health School have found that pancreatic cancer causes systemic disorders throughout the body. Loss of muscle, fat abrasion and vital organs. These processes are the basis for hanging. Review results have been published in Hlife magazine.
The suspension is a pathological state characterized by severe body loss. Unlike ordinary hunger, the suspension is not compensated by the addition of food. To understand how the pancreatic cancer causes this process, scientists have analyzed laboratory and clinical data.
They have discovered several main factors, cytokins (TNF-α, IL-6) that cause chronic inflammation, TGF-β family growth factors (asset A, GDF15), which suppress the muscle growth, and microscopic balloons, through which the tumor signals sends signals to other tissues.
Under their influence, the muscles are activated by the Wbikwitin Protease path, a protein corruption system. During this process, MAFBX and Murf1 enzymes begin to decay muscle while ATGL and HSL decompose fat. The resulting acids nourish the tumor and accelerate the patient's exhaustion.
Moreover, scientists emphasize that the hanger affects not only muscles and fat. It also affects the liver, the brain and the immune system, creating a vicious circle of metabolic disorders.
"This article is rewritten by the suspension, not as a symptom, but as a syndrome of cancer, and the whole body affecting the whole body," one of the authors of the study, Professor Venming Wu.
According to him, the understanding of molecular mechanisms allows us to identify new targets of diagnosis and treatment.
Translation of: Euromedia24.com
