The combination of natural materials, nicotinamide (a form of vitamin B3) and green tea, can combat the galati a combination of Alzheimer's disease. This conclusion was reached by the scientists from the University of California of Irvin. The results of the study were published in the Geroscience magazine.
In laboratory conditions, such therapy has restored Guanozin Triphosphate (GTP) in the aging neurons of mice and activated the mechanisms of self-cleaning brain. The combination of materials also helped neurons get rid of amyloid proteins, which are one of the main signs of Alzheimer's disease.
"With age, the brain loses the ability to use damaged ingredients. We found that the GTP level raising helps to restore this function, "explained the study of the study by Gregory Brier.
Scientists have used the Geval fluorescent sensor to measure the GTP level in neurons of the elderly mice. It turned out that the mitochondries, cell energy centers, especially severely suffered their age. This disrupts autophagia, the process through which cells are cleaned of damage.
However, only 24 hours after the nicotinamide and epigalocatech treatment, the GTP level returned to the values of young cells in aging neurons. As a result, the main proteins were activated, energy metabolism was improved, and the erca-amyloid sediments were efficiently removed.
According to researchers, GTP can be important but previously underestimated targeting age brain disorders. However, as Brothers mentioned, additional research is needed to find the optimal supply of compounds. The scientist explained that in the form of a pill (oral) nicotinamid rapidly inactivated the body, which reduces the effectiveness of treatment.
Translation of: Euromedia24.com
