Scientists from Medical School after Lewis found that PSAT1 Activation stimulates the restoration of heart tissue near the adults of heart attacks. The results of the study were published in Theranostics magazine.
PSAT1 gene participates in the growth of cells in the embryonic period, but in adults it is practically inactive. Researchers have created modified MRNA containing this gene and import it into mice heart tissue immediately after heart attack. This has led to the activation of cardiocytes (heart muscle cells), reducing tissue consolation and the emergence of new blood vessels. As a result, animal function has improved significantly.
Scientists have explained that Psat1 stimulates the synthesis of Seri, Amino acid, which plays an important role in protecting cells from stress and restoring DNA. The main link of the action mechanism was YAP1 protein, known for its ability to promote recovery processes. Without it, the impact of PSAT1 acceptance was disappearing.
The study used in the study Modrna (Modified Messenger RNA) has previously been used to develop MRA vaccines against Covid-19. According to researchers, it allows the genetic material to bring cells without changing the DNA, which reduces possible risks.
According to the authors of the work, this approach can be a basis for new cardural insufficiency methods in which the organ is not only supported, but also restores.
Translation of: Euromedia24.com
