Scientists from St. James Hospital (Ireland) have found that Covid-19 medicine Dexamethazone can intensify immune cells, infection, including the tuberculosis. The results of the study were published in Scientific Reports (Scirep).
Dexamethawone belongs to the class of glucocorticoids, hormonal medicines, which pressure, but can also weaken the immune response. For this reason, glucocorticoids are considered to treat potentially risky infectious diseases, as in some cases they can reactivate the hidden tuberculosis infection.
However, the World Health Organization recommends glucocorticoids in certain clinical situations as additional tuberculosis therapy.
For the study, scientists have treated the blood of healthy donors and the macrofags of the pyramid fluid with diaphethason. The cells were then infected with mycobacterium tuberculosis.
The results show that the drug reduces the level of inflammatory signal molecules, while helping macrofags survive and destroy bacteria. This effect is related to the activation of autophagish, the process of waste processing in cells.
Scientists have said that the macrophager responded from different sources to Dexamethazon. This shows the importance of cell tissue origin when evaluating the effectiveness of therapy.
These data are confirmed by the idea of using additional therapy into tuberculosis, in particular, in cases of heavy inflammation, where it is important to reduce the damage to the tissue without disrupting immune protection.
Translation of: Euromedia24.com
