The scientists from the University of Edinburgh have discovered eight regions of genome related to the development of Malgic Encephalomielitis or Chronic Fatigue Syndrome (CSF). This was reported by The Guardian.
More than 275,000 people from the United Kingdom have participated in the project. Among the researchers, 15.5 thousand people were diagnosed with CSF, and the remaining 260,000 were a healthy control group. DNA comparative analysis has allowed scientists to identify eight genomic regions, which were significantly different in patients with chronic fatigue.
"We have discovered eight genetic signals that testify to both immune and nervous systems," said Kris Ponting, Head of the Research.
According to him, the activity of the relevant genes is mainly concentrated in the brain tissue, which emphasizes the role of the central nervous system in the development of the disease.
Scientists have also discovered 43 genes that affect the risk of developing chronic fatigue. 29 of them were the most promising for further studies. The activation of one of them, Rabgap1L, as noted by patients, was reliably connected with the decline in immunity.
Despite the fact that chronic fatigue is more often diagnosed with women, the study has not identified any difference between genetic risks between sex. The next step will be a detailed study of DNA sections. Scientists hope to find out how these genetic features affect the molecular and mobile processes of the body. In the future, this can lead to the creation of new diagnostic tests and new methods of treatment.
Translation of: Euromedia24.com
