The scientists of the Institute of Immunobiology and Epigenetics after Max Planck have first made a complete map of metabolism and molecular changes in human bloodstream cells. One of the main discoveries was that the level of important nutrients, cholini is high in healthy and young cells, but decreases with aging and diseases. In the laboratory, Kholini supplements have contributed to the restoration of the "youth" properties of cells. The work was published in the Nature Cell Biology (NCB) magazine.
Blood-shaped stem cells meet in bone marrow and can cause all types of blood. They are extremely rare, and that's why it was difficult to get the full picture of their metabolic activity. In a new study, scientists have used sensitive technologies that allow you to analyze hundreds of molecules on a very small number of cells. This allowed compare metabolic data to gene activity and track how the cell changes with aging and oncological conversions.
One of the main results was that young stem cells were less active in terms of metabolism than their specialized generations. They produce less energy and building materials for cells, which helps them stay "calm" and be able to recover. However, along with aging and the development of Leukemia, these cells lose a number of basic functions, including the decline in the level of cholini.
Kholin, for example, is found in eggs, soybeans and fish. During the experiment, Kolin's supplements helped the stem cells to restore the lipid metabolism and maintain their characteristics closer to the potential benefits of diet and metabolism in the treatment of blood disorders and health care.
The study lays the groundwork for the new strategies for extending the "healthy youth" of the entire blood-created apparatus. In the future, this can lead to more effective support for elderly patients, as well as developing new approaches to the fight against Leukemia.
Translation of: Euromedia24.com
