Scientists from the Novosibirsk State University of Novosibirsk Institute of Organic Chemistry, as well as Irish partners, have proven to be a major anti-cancer activity of the Chemical Compounds, which can be a basis for creating a new anti-tumor drug, NSU reports.
Currently, the main way to treat cancer remains chemotherapy, but one of the main reasons for the active search for new treatment methods is the serious side effects of some drugs. In addition, cancer cells can avoid the impact of the drug through a number of mechanisms. One of the promising areas here is peptide therapy.
"Researchers have proven high anti-cancer activity in a chemical compound, which includes cational antimicrobial peptides (AMP), which are also called host defense peptides. In the future, this compound can be a basis for creating a new effective anti-tumultural drug, "the report said.
The university explained that the work lasted for several years, but as a result, scientists were able to show the high activity of such compounds on the crops of tumor cells. In addition, it was possible to explore the mechanisms of its action at the molecular level, this is a precondition for registering any new anti-cancer drug at the global level.
In the past, the AMP combination with a bioactive molecule has shown good results in creating antimicrobial drugs. It turned out that some peptides are specifically recognized and connected to the proteins of the membrane of the tumor cells, using anti-tumor effect. The scientists have used this feature in their research.
Translation of: Manuel Tamazyan
